It is one of the more striking generalizations of biochemistry - which surprisingly is hardly ever mentioned in the biochemical textbooks - that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.

Quote by Francis Crick

Topics: Francis Crick Quotes

If, for example, all the codons are triplets, then in addition to the correct reading...

If, for example, all the codons are triplets, then in addition to the correct reading...

The meaning of this observation is unclear, but it raises the unfortunate possibility of ambiguous...

The meaning of this observation is unclear, but it raises the unfortunate possibility of ambiguous...

Attempts have been made from a study of the changes produced by mutation to obtain...

Attempts have been made from a study of the changes produced by mutation to obtain...

This seems highly likely, especially as it has been shown that in several systems mutations...

This seems highly likely, especially as it has been shown that in several systems mutations...

A comparison between the triplets tentatively deduced by these methods with the changes in amino...

A comparison between the triplets tentatively deduced by these methods with the changes in amino...

A final proof of our ideas can only be obtained by detailed studies on the...

A final proof of our ideas can only be obtained by detailed studies on the...

For simplicity one can think of the + class as having one extra base at...

For simplicity one can think of the + class as having one extra base at...

How is the base sequence, divided into codons? There is nothing in the backbone of...

How is the base sequence, divided into codons? There is nothing in the backbone of...

The balance of evidence both from the cell-free system and from the study of mutation,...

The balance of evidence both from the cell-free system and from the study of mutation,...

Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than...

Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than...

It has yet to be shown by direct biochemical methods, as opposed to the indirect...

It has yet to be shown by direct biochemical methods, as opposed to the indirect...

Do codons overlap? In other words, as we read along the genetic message do we...

Do codons overlap? In other words, as we read along the genetic message do we...

It now seems certain that the amino acid sequence of any protein is determined by...

It now seems certain that the amino acid sequence of any protein is determined by...

It would appear that the number of nonsense triplets is rather low, since we only...

It would appear that the number of nonsense triplets is rather low, since we only...

Moreover the incorporation requires the same components needed for protein synthesis, and is inhibited by...

Moreover the incorporation requires the same components needed for protein synthesis, and is inhibited by...

It seems likely that most if not all the genetic information in any organism is...

It seems likely that most if not all the genetic information in any organism is...

If poly A is added to poly U, to form a double or triple helix,...

If poly A is added to poly U, to form a double or triple helix,...

It now seems very likely that many of the 64 triplets, possibly most of them,...

It now seems very likely that many of the 64 triplets, possibly most of them,...